| 1 |
The Institute of Zoology, Regent's Park, London NW1 4RY, UK.
Corresponding author, phone: 020-7449-6617, Fax: 020-7586-2870, email:Matthew.Fisher@ioz.ac.uk |
| 2 | Roche Molecular Systems, 1145 Atlantic Avenue, Alameda, CA 94501 |
| 3 | Department of Plant and Microbial Biology, University of California, Berkeley, California, 94720-3102 |
Coccidioides posadasii sp. nov., formerly known as non-California (non-CA) Coccidioides immitis, is described. Phylogenetic analyses using single nucleotide polymorphisms, genes, and microsatellites show that C. posadasii represents a divergent, genetically recombining monophyletic clade. Coccidioides posadasii can be distinguished from C. immitis by numerous DNA polymorphisms, and we show how either of two microsatellite loci may be used as diagnostic markers for this species. Growth experiments show that C. posadasii has significantly slower growth rates on high-salt media when compared with C. immitis, suggesting that other phenotypic characters may exist.© Copyright by The Mycological Society of America 2002Keywords: allele, Coccidioidomycosis, microsatellite, Onygenales, phylogeny, systematics.